题目：Highly Fluorescent Semiconducting Polymer Dots for Biological Imaging and Sensing Applications
时间：2014年12月8日（周一）上午10：00-11：30
地点：光电工程学院三楼多功能厅
报告人：吴长锋 教授（吉林大学）
主持人： 许改霞 副教授
摘要：
Semiconducting polymer nanoparticles have attracted considerable interest due to their outstanding properties as fluorescent probes. These nanoparticles are called polymer dots (Pdots) when they exhibit small particle size and high brightness. Quantitative comparisons of the optical properties of the Pdots indicate their fluorescence brightness is a factor of 102~104 higher than conventional fluorescent dyes, and a factor of 10~103 than inorganic quantum dots. Single particle fluorescence imaging and kinetic studies indicate much higher emission rates of the Pdots as compared to quantum dots, and but no “blinking” as often encountered for fluorescent dye and quantum dots. In addition, efficient intra-particle energy transfer has been demonstrated in fluorescent dye-doped Pdots, which provides a new strategy to improve the fluorescence brightness and photostability of the Pdots, and design novel sensitive biosensors. In this presentation, we summarize recent findings of the photophysical properties of Pdots and their applications in cellular labeling, in vivo fluorescence imaging, photoacoustic imaging, and versatile biosensors.
报告人简历：
吴长锋，教授，博导，吉林大学。2004年获中科院长春光机所凝聚态物理博士学位。2008年获Clemson大学化学博士学位，期间与导师Jason McNeill合作在国际上开展了半导体聚合物作为荧光量子点的研究工作，系统研究了半导体聚合物量子点的制备表征、能量传递、及单粒子荧光等性质。 2008年赴华盛顿大学Daniel T. Chiu研究组从事博士后研究，在聚合物量子点的生物功能化、特异性细胞标记、及动物在体肿瘤成像等方面开展了研究。2011年入选国家首批青年计划，2012年获得国家自然科学优秀青年基金，2013年获国家自然科学基金重点项目资助。迄今共发表SCI收录论文70余篇，SCI论文已总共被他引2800多次，当前H因子为28。
